Clik here to view.
Different Cancers Can Share Genetic Signatures
NIH-funded researchers analyzed the DNA of these cancers. Cancer is a disease of the genome. It arises when genes involved in promoting or suppressing cell growth sustain mutations that disturb the...
View ArticleClik here to view.
Creative Minds: Interpreting Your Genome
Credit: Jane Ades, National Human Genome Research Institute, NIH Just this year, we’ve reached the point where we can sequence an entire human genome for less than $1,000. That’s great news—and rather...
View ArticleClik here to view.
Creative Minds: Engineering Targeted Breast Cancer Treatments
Debra Auguste A few years ago, Debra Auguste, a chemical engineer then at Harvard University, was examining the statistics on breast cancer: the second most common cancer in women in the U.S. after...
View ArticleClik here to view.
Weighing Surgical Options for Breast Cancer
Stock image An increasing number of women with cancer in one breast are choosing to have both breasts surgically removed in hopes of reducing the chance of developing cancer in the unaffected breast....
View ArticleClik here to view.
Creative Minds: Tackling Chemotherapy Resistance
Aaron Meyer For many young scientists, nothing can equal the chance to have a lab of one’s own. Still, it often takes considerable time to get there. To help creative minds cut to the chase sooner, the...
View ArticleClik here to view.
Creative Minds: Michael Angelo’s Art
Caption: The location and abundance of six proteins—e-cadherin (green), vimentin (blue), actin (red), estrogen receptor, progesterone receptor, and Ki67—found in breast cancer cells are seen in this...
View ArticleClik here to view.
Hereditary Breast and Ovarian Cancers: Moving Toward More Precise Prevention
Caption: “Homologous Hope” sculpture at University of Pennsylvania depicting the part of the BRCA2 gene involved in DNA repair.Credit: Dan Burke Photography/Penn Medicine Inherited mutations in the...
View ArticleClik here to view.
LabTV: Curious About Cancer Patients’ Quality of Life
Katie Martinez struggled mightily with math in high school, but now she’s eagerly pursuing a biomedical research career that’s all about crunching numbers. So, what happened to Katie? Cancer is what...
View ArticleClik here to view.
Cancer Metastasis: Trying to Catch the Culprits Earlier
Caption: Scaffold of a cancer cell-attracting implant as seen by scanning electron microscopy. Credit: Laboratory of Lonnie Shea For many people diagnosed with cancer localized to the breast, prostate,...
View ArticleClik here to view.
Cool Videos: Spying on Cancer Cell Invasion
If you’re a fan of the Mission: Impossible spy thrillers, you might think that secret agent Ethan Hunt has done it all. But here’s a potentially life-saving mission that his force has yet to...
View ArticleClik here to view.
Snapshots of Life: Finding a Cube for Cancer
Jenolyn F. Alexander and Biana Godin, Houston Methodist Research Institute; Veronika Kozlovskaya and Eugenia Kharlampieva, University of Alabama at Birmingham. Creative photographers have long...
View ArticleClik here to view.
Tumor Scanner Promises Fast 3D Imaging of Biopsies
Caption: University of Washington team that developed new light-sheet microscope (center) includes (l-r) Jonathan Liu, Adam Glaser, Larry True, Nicholas Reder, and Ye Chen.Credit: Mark Stone/University...
View ArticleClik here to view.
New ‘Liquid Biopsy’ Shows Early Promise in Detecting Cancer
Caption: Liquid biopsy. Tumor cells shed protein and DNA into bloodstream for laboratory analysis and early cancer detection. Early detection usually offers the best chance to beat cancer....
View ArticleClik here to view.
Most Women with Early-Stage Breast Cancer Don’t Need Chemo
Credit: National Cancer Institute, NIH In the last few days, you may have heard that there’s been a significant development in the management of breast cancer. So here’s the NIH Director’s blog...
View ArticleA Scientist Whose Music Gives Comfort
Over the past few years, my blog has highlighted a wide range of Creative Minds from across biomedical research. But creative minds come in many forms, and, for a change of pace, I’d like to kick back...
View ArticleClik here to view.
3D Action Film Stars Cancer Cell as the Villain
breastcacell-mp4 For centuries, microscopes have brought to light the otherwise invisible world of the cell. But microscopes don’t typically visualize the dynamic world of the cell within a living...
View ArticleClik here to view.
Putting Bone Metastasis in the Spotlight
When cancers spread, or metastasize, from one part of the body to another, bone is a frequent and potentially devastating destination. Now, as you can see in this video, an NIH-funded research team...
View ArticleClik here to view.
Using MicroRNA to Starve a Tumor?
Credit: Dudley Lab, University of Virginia School of Medicine, Charlottesville Tumor cells thrive by exploiting the willingness of normal cells in their neighborhood to act as accomplices. One of...
View ArticleClik here to view.
Body-on-a-Chip Device Predicts Cancer Drug Responses
Credit: McAleer et al., Science Translational Medicine, 2019 Researchers continue to produce impressive miniature human tissues that resemble the structure of a range of human organs, including the...
View ArticleClik here to view.
Panel Finds Exercise May Lower Cancer Risk, Improve Outcomes
Credit: gettyimages/vgajic Exercise can work wonders for your health, including strengthening muscles and bones, and boosting metabolism, mood, and memory skills. Now comes word that staying active...
View ArticleCaught on Video: Cancer Cells in Act of Cannibalism
Tumors rely on a variety of tricks to grow, spread, and resist our best attempts to destroy them. Now comes word of yet another of cancer’s surprising stunts: when chemotherapy treatment hits hard,...
View ArticleGiving Thanks for Biomedical Research
This Thanksgiving, Americans have an abundance of reasons to be grateful—loving family and good food often come to mind. Here’s one more to add to the list: exciting progress in biomedical research....
View ArticleClik here to view.
Insurance Status Helps Explain Racial Disparities in Cancer Diagnosis
Credit: iStock/jmangostock Women have the best odds of surviving breast cancer if their disease is caught at an early stage, when treatments are most likely to succeed. Major strides have been made in...
View ArticleClik here to view.
Tackling Cancer Metastasis with Engineered Blood Platelets
Tara DeansCredit: Dan Hixson/University of Utah College of Engineering, Salt Lake City When cancer cells spread to new parts of the body in a process called metastasis, they often get there by...
View ArticleClik here to view.
Welcoming First Lady Jill Biden to NIH!
It was wonderful to have First Lady Jill Biden pay a virtual visit to NIH on February 3, 2021, on the eve of World Cancer Day. Dr. Biden joined me, National Cancer Institute (NCI) Director Ned...
View ArticleClik here to view.
On-the-Spot Gene Readouts Offer Clues to How Cells Work
Credit: MIT and Harvard Medical School, Cambridge, MA Just as two companies can merge to expand their capabilities, two technologies can become more powerful when integrated into one. That’s why...
View Article
